Trypanocidal activity of genotoxic concentration of benznidazole on epimastigote forms of Trypanosoma cruzi
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چکیده
منابع مشابه
Trypanocidal Activity of Some Medicinal Plants Against the Epimastigotes of Trypanosoma cruzi
Background: Some of medicinal plants are a potential source of new drugs to improve the treatment of Chagase disease whose treatment is still a challenge. Here in this screening, the in vitro trypanocidal activity of some fractions for 16 medicinal plants, collected from the northern part of Iran, has been reported. Methods: Aerial parts of the plants were dried carefully and followed by ex...
متن کاملStructural analysis of inositol phospholipids from Trypanosoma cruzi epimastigote forms.
Inositol phospholipids (IPL) from epimastigote forms of Trypanosoma cruzi have been investigated by metabolic labelling with [3H]palmitic acid and by GLC-MS analysis of the lipids obtained from non-labelled parasites. The IPL fraction was separated into phosphatidylinositol (PI) and inositol-phosphoceramide subfractions, the latter accounting for 80-85% of the total IPL. The neutral lipids rele...
متن کاملAnti-Trypanosoma cruzi activity of extracts from Argentinean Asteraceae species
The anti-Trypanosoma cruzi activity of extracts from 13 Argentinean Asteraceae species was determined. Dichloromethane and methanol extracts of Acmella bellidioides, Aspilia silphioides, Viguiera tuberosa, Calyptocarpus biaristatus, Hyalis argentea, Helenium radiatum, Gaillardia megapotamica, Verbesina subcordata, Gymnocoronis spilanthoides, Viguiera anchusaefolia, Thelesperma megapotamicum, Ze...
متن کاملPrimary structure of the oligosaccharide chain of lipopeptidophosphoglycan of epimastigote forms of Trypanosoma cruzi.
The lipopeptidophosphoglycan of epimastigote forms of Trypanosoma cruzi is composed of a glycan linked through a non-N-acetylated glucosamine residue to an inositol phosphorylceramide. Using conventional analysis techniques, including 1H, 13C, and 31P NMR spectroscopy and negative ion fast atom bombardment mass spectroscopy, the structure of the carbohydrate-containing part of the molecule is d...
متن کاملAnti-Trypanosoma cruzi activity of extracts from Argentinean Asteraceae species
The anti-Trypanosoma cruzi activity of extracts from 13 Argentinean Asteraceae species was determined. Dichloromethane and methanol extracts of Acmella bellidioides, Aspilia silphioides, Viguiera tuberosa, Calyptocarpus biaristatus, Hyalis argentea, Helenium radiatum, Gaillardia megapotamica, Verbesina subcordata, Gymnocoronis spilanthoides, Viguiera anchusaefolia, Thelesperma megapotamicum, Ze...
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ژورنال
عنوان ژورنال: Acta Scientiarum. Health Science
سال: 2012
ISSN: 1807-8648,1679-9291
DOI: 10.4025/actascihealthsci.v34ispec.12337